AST (aspartate aminotransferase) is an
This article discusses the test to measure the amount of AST in the blood.
Aspartate aminotransferase; Serum glutamic-oxaloacetic transaminase; SGOT
How the test is performed
A blood sample is needed. It is usually taken from a vein. This is called a
How the test will feel
When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.
Why the test is performed
This test is mainly done along with other tests (such as
The normal range is 10 to 34 IU/L.
Note: IU/L = international units per liter
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens.
What abnormal results mean
Increased AST levels are usually a sign of liver disease. Liver disease is even more likely if other liver-related blood tests are abnormal.
An increase in AST levels may be due to:
Cirrhosis(scarring of the liver)
- Death of liver tissue
Heart attack Hemochromatosis Hepatitis
- Lack of blood flow to the liver (liver ischemia)
- Liver cancer or tumor
- Medicines that are toxic to the liver
- Muscle disease or trauma
Pancreatitis(swollen and inflamed pancreas)
AST levels may also increase after:
What the risks are
Veins vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Risks associated with having blood drawn are slight but may include:
Bleeding from where the needle was inserted
- Fainting or feeling light-headed
- Hematoma (blood collecting under the skin)
- Infection (a slight risk any time the skin is broken)
AST levels may rise during pregnancy and after exercise.