Hallervorden-Spatz disease is a movement disorder that is passed down through families (inherited).
Pantothenate kinase-associated neurodegeneration
Causes, incidence, and risk factors
Hallervorden-Spatz disease usually begins in childhood.
Most cases of Hallervorden-Spatz disease are due to a defect in a gene that makes a protein called pantothenate kinase 2. Patients with this genetic defect have a buildup of iron in parts of the brain.
Involuntary muscle contractions (
Muscle rigidity Seizures Spasticity
- Vision changes
- Writhing movements
Signs and tests
The doctor or nurse will examine you and ask questions about your symptoms and medical history. The exam may show:
Abnormal postures and movements
Genetic tests can look for the defective gene that causes the disease. However, this test is not yet widely available. It is only found at certain research laboratories.
Tests such as
There is no specific treatment for Hallervorden-Spatz disease. Treatment is focused on controlling the symptoms.
Hallervorden-Spatz gets worse and damages the nerves over time. It leads to a lack of movement and often death by early adulthood.
Medication used to treat symptoms can cause complications. Being unable to move from the disease can lead to:
Calling your health care provider
Call your health care provider if your child develops:
Increased stiffness in the arms or legs
Increasing problems at school
Genetic counseling is appropriate in families affected by this illness. There is no known way to prevent it.