Definition

Post-splenectomy syndrome is a group of symptoms and signs that often occur after surgery to remove the spleen (splenectomy).

These include:

  • Destruction of red blood cells
  • Increased risk of getting severe infections, especially with certain bacteria, such as Streptococcus pneumoniae and Neisseria meningitidis
  • Thrombocytosis (increased platelet count, which can cause blood clots)

Alternative Names

Splenectomy – post-surgery syndrome

Complications

Possible long-term medical problems include:

  • Hardening of the arteries (atherosclerosis)
  • Pulmonary hypertension (a disease affecting the blood vessels in your lungs)
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