Secondary amenorrhea occurs when a woman who has been having normal menstrual cycles stops getting her periods for 6 or more months.
Women who are pregnant, breastfeeding, or in menopause are not considered to have secondary amenorrhea.
Amenorrhea – secondary; No periods – secondary; Absent periods – secondary; Absent menses – secondary; Absence of periods – secondary
Causes, incidence, and risk factors
Women who are taking birth control pills or who receive hormone shots such as Depo-Provera may not have any monthly bleeding. When they stop taking these hormones, their periods may not return for more than 6 months.
You are more likely to have amenorrhea if you:
- Are obese
- Exercise too much and for long periods of time
- Have very low body fat (less than 15% – 17%)
- Have severe anxiety or emotional distress
- Lose a lot of weight suddenly (such as with strict or extreme diets or after
gastric bypass surgery)
Other causes include:
- Brain (pituitary) tumors
- Chemotherapy drugs for cancer
- Drugs used to treat
schizophreniaor psychosis Overactive thyroid gland Polycystic ovarian syndrome
- Reduced function of the ovaries
Also, procedures such as a dilation and curettage (
In addition to having no menstrual periods, other symptoms can include:
- Breast size changes
Weight gainor weight loss
- Discharge from the breast (
galactorrhea) or change in breast size
- Increased hair growth in a “male” pattern (
hirsutism) and acne
- Vaginal dryness
- Voice changes
If amenorrhea is caused by a pituitary tumor, there may be other symptoms related to the tumor, such as vision loss and
Signs and tests
A physical exam and pelvic exam must be done to check for pregnancy. A
Blood tests may be done to check hormone levels, including:
Estradiol levels Follicle stimulating hormone(FSH level) Luteinizing hormone(LH level) Prolactin level
hormone levelssuch as testosteronelevels Thyroid stimulating hormone(TSH)
Other tests that may be performed include:
CT scanor MRI scan of the headto look for tumors Biopsy of the lining of the uterus
- Genetic testing
- Ultrasound of the pelvis or
Treatment depends on the cause of the amenorrhea. Normal monthly periods usually return after the condition is treated.
A lack of menstrual period due to
The outlook depends on the cause of amenorrhea. Many of the conditions that cause secondary amenorrhea will respond to treatment.
Calling your health care provider
Call for an appointment with your primary health care provider or women’s health provider if you have missed more than one period so that you can get diagnosed and treated, if necessary.