Toxic nodular goiter involves an enlarged thyroid gland that contains rounded growths called nodules. These nodules produce too much thyroid hormone.
Toxic multinodular goiter; Plummer’s disease
Causes, incidence, and risk factors
Toxic nodular goiter grows from an existing
Sometimes patients with toxic multinodular goiter will develop high thyroid levels for the first time after they receive a large amount of iodine through a vein (intravenously). The iodine may be used as contrast for a
Symptoms are those of an overactive thyroid gland (
- Frequent bowel movements
- Increased appetite
- Increased sweating
- Irregular menstrual period (in women)
- Weight loss
Signs and tests
Other tests that may be done:
Serum thyroid hormone levels (
Serum TSH(thyroid stimulating hormone) Thyroid scan
Antithyroid drugs (propylthiouracil, methimazole)
Beta-blockers (propranolol) can control some of the symptoms of hyperthyroidism until thyroid hormone levels in the body are under control.
Because toxic nodular goiter is mainly a disease of the elderly, other
Congestive heart failure
Irregular heartbeat (
Rapid heart rate
Bone loss leading to
Thyroid crisis or storm is an
Decreased mental alertness
People with this condition need to go to the hospital right away.
Complications of having a very large goiter may include difficulty breathing. This is due to pressure on the airway passage that lies behind the thyroid.
Calling your health care provider
Call your health care provider if you have symptoms of this disorder. Follow the health care provider’s recommendations for follow-up visits.
To prevent toxic nodular goiter, treat hyperthyroidism and simple goiter as your health care provider recommends.