Tropical sprue is a condition seen in residents of, or visitors to, tropical areas. It impairs the absorption of nutrients from the intestines, causing
Causes, incidence, and risk factors
This disease is caused by inflammation of, and damage to the small intestine due to having too much of certain types of bacteria in the intestines.
Risk factors are:
Living in the tropics
Long periods of travel to tropical destinations
- Diarrhea, worse on high-fat diet
Excessive gas (flatus) Indigestion
Muscle cramps Numbness Paleness Weight loss
Signs and tests
Bone density test
- Complete blood count (
CBC) Comprehensive metabolic panel Enteroscopy
- Folate level (serum)
- Iron level (serum)
- Stool examination for bacteria and parasites
endoscopy Upper GI series Vitamin B12 level(serum)
- Vitamin D level
Treatment begins with plenty of fluids and electrolytes. Replacement of folate, iron, vitamin B12, and other nutrients may also be needed. Antibiotic therapy with tetracycline or another broad-spectrum antibiotic is given at the beginning of treatment.
Oral tetracycline is usually not prescribed for children until after all of their permanent teeth have appeared, because it can permanently discolor teeth that are still forming. However, other antibiotics are available.
The outcome is good with treatment.
Vitamin and mineral deficiencies are common complications.
In children, sprue leads to:
Delay in the maturing of bones (skeletal maturation)
Calling your health care provider
Call your health care provider if:
- Tropical sprue symptoms get worse or do not improve with treatment
- You develop new symptoms
- You have diarrhea or other symptoms of this disorder for a long period of time, especially after spending time in the tropics
Other than avoiding living in or traveling to tropical climates, there is no known prevention for tropical sprue.