Ureteral retrograde brush biopsy is a procedure in which tissue from the lining of the kidney or ureter (tube that connects a kidney to the bladder) is removed for examination.
Biopsy – brush – urinary tract; Retrograde ureteral brush biopsy cytology; Cytology – ureteral retrograde brush biopsy
How the test is performed
This procedure is performed using regional (spinal) or
A tube with a camera on the end (
The cystoscope is removed, leaving the guide wire in place. A longer, thinner telescope (ureteroscope) with a small camera is then inserted over or next to the guide wire to see the inside of the ureter or kidney.
A nylon or steel brush is placed through the ureteroscope. The suspicious area is rubbed with the brush. Biopsy forceps may be used instead to collect a tissue sample.
The brush or biopsy forceps is removed. The tissue is taken from the instrument and sent to a pathology laboratory for analysis. The instrument and guide wire are removed from the body. Sometimes a small tube or stent is temporarily left in the ureter to prevent a kidney blockage caused by swelling from the procedure.
How to prepare for the test
You will probably need to fast for about 6 hours. Your health care provider will tell you how you need to prepare.
How the test will feel
After the test is over, you may have some mild cramping or discomfort. Some burning may occur the first few times you empty your bladder. You may also see some blood in your urine for a few days after the procedure.
Why the test is performed
This test is used to take a sample of tissue from the kidney (
The tissue appears normal.
What abnormal results mean
Abnormal results may show cancerous cells (
What the risks are
- Allergy to anesthesia
- Hole (perforation) in the ureter
- Infection (
urinary tract infection, pyelonephritis, or sepsis)
Tell your health care provider if you have an allergy to seafood — it may cause an
This test should not be performed in people with a urinary tract infection or a blockage at or below the biopsy site.
After the test, watch for
A small amount of