An atrial myxoma is a noncancerous tumor in the upper left or right side of the heart. It grows on the wall that separates the two sides of the heart. This wall is called the atrial septum.
Causes, incidence, and risk factors
A myxoma is a primary heart (cardiac) tumor. This means that the tumor started within the heart. Most heart tumors start somewhere else.
Primary cardiac tumors are rare. Myxomas are the most common type of these rare tumors. About 75% of myxomas occur in the left atrium of the heart, usually beginning in the wall that divides the two upper chambers of the heart. The rest are in the right atrium. Right atrial myxomas are sometimes associated with tricuspid stenosis and
Myxomas are more common in women. About 1 in 10 myxomas are passed down through families (inherited). Such tumors are called familial myxomas. They tend to occur in more than one part of the heart at a time, and often cause symptoms at a younger age.
Symptoms may occur at any time, but most often they go along with a change in body position.
Symptoms of a myxoma may include:
Breathing difficulty when lying flat Breathing difficulty when asleep Chest painor tightness Dizziness Fainting
- Sensation of feeling your heart beat (
palpitations) Shortness of breathwith activity
The symptoms and signs of left atrial myxomas often mimic
Right atrial myxomas rarely produce symptoms until they have grown to be at least 5 inches wide.
Other symptoms may include:
Blueness of skin, especially the fingers (Raynaud’s phenomenon)
- Curvature of nails accompanied with soft tissue swelling (
clubbing) of the fingers
Fingers that change color upon pressureor with cold or stress
- General discomfort (
- Losing weight without trying
- Swelling – any part of the body
Signs and tests
The doctor or nurse will perform a physical exam and listen to your heart using a tool called a stethoscope. Abnormal heart sounds or a murmur may be heard. These sounds may change when you change body position.
Imaging tests may include:
Chest x-ray CT scan of chest ECG
Doppler study Heart MRI Left heart angiography Right heart angiography
Surgery is needed to remove the tumor. Some patients will also need their mitral valve replaced. This can be done during the same surgery.
Myxomas may come back if surgery did not remove all of the tumor cells.
Although a myxoma is not cancer, complications are common.
Untreated, a myxoma can lead to an
If the tumor grows inside the heart, it can block blood flow. This may require emergency surgery to prevent sudden death.
Arrhythmias Pulmonary edema
- Spread (
metastasis) of the tumor
- Blockage of the mitral heart valve