The CSF-VDRL test is used to help diagnose
Venereal disease research laboratory slide test – CSF
How the test is performed
A sample of spinal fluid is needed. For information on how this is taken, see:
Why the test is performed
The CSF-VDRL test is done to diagnose syphilis in the brain or spinal cord. Brain and spinal cord involvement is usually a sign of late stage syphilis.
Blood screening tests (VDRL and RPR) are better at detecting middle stage (secondary) syphilis.
A negative result is normal.
However, false-negatives can occur. This means you can have syphilis even if this test is normal. Therefore, a negative test does not always rule out the infection. Other signs and tests may be used to diagnose neurosyphilis.
What abnormal results mean
A positive result is abnormal and is a sign of neurosyphilis.