Ganglioneuroblastoma is an intermediate tumor that grows nerve tissue. An intermediate tumor is one that is between benign (slow-growing and unlikely to spread) and malignant (fast-growing, aggressive, and likely to spread).
Causes, incidence, and risk factors
This rare tumor occurs in less than 5 out of every 1,000,000 children each year.
Tumors of the nervous system have different degrees of differentiation. The degree of differentiation is based on how the tumor cells look under the microscope. It can predict whether or not they are likely to spread.
Benign tumors are less likely to spread. Malignant tumors are aggressive, grow quickly, and often spread. A
A ganglioneuroblastoma may be only in one area or it may be widespread, but it is usually less aggressive than a neuroblastoma. The cause is unknown.
Most commonly, a lump can be felt in the abdomen. However, this condition may also occur in other parts of the body.
Signs and tests
- Bone marrow aspiration and biopsy
- Bone scan
- CT scan or MRI scan of the affected area
- Special blood and urine tests
- Surgical biopsy to confirm diagnosis
Because these tumors are rare, they should be treated in a specialized center by experts who have experience with them.
Depending on the type of tumor, treatment can involve surgery, and possibly chemotherapy and radiation therapy.
You can often help the
The outlook depends on how far the tumor has spread, and whether some areas of the tumor contain more aggressive cancer cells.
Complications of surgery,
radiation, or chemotherapy
Spread of the tumor into surrounding areas
Calling your health care provider
Call your health care provider if you feel a lump or growth on your child’s body. Make sure children receive routine examinations as part of their well-child care.