Hereditary ovalocytosis is rare condition passed down through families (inherited) in which blood cells are slightly oval-shaped instead of round. It is a form of
Ovalocytosis – hereditary
Causes, incidence, and risk factors
Ovalocytosis is mainly found in Southeast Asian populations.
Newborn infants with ovalocytosis may have anemia and jaundice. Adults usually do not show symptoms and are known as asymptomatic.
Signs and tests
An examination by your health care provider may occasionally show an enlarged spleen.
This condition is diagnosed by looking at the shape of blood cells under a microscope. The following tests may also be done:
Complete blood count(CBC) to check for anemia or red blood cell destruction
- Blood smear to determine cell shape
Bilirubin level(may be high)
- Lactate dehydrogenase level (may be high)
- Ultrasound of the abdomen (may show gallstones)
In severe cases, the disease may be treated by removal of the spleen (
The condition may be associated with gallstones or kidney problems.