Uveitis is swelling and irritation of the
Iritis; Pars planitis; Choroiditis; Chorioretinitis; Anterior uveitis; Posterior uveitis
Causes, incidence, and risk factors
The most common form of uveitis is anterior uveitis, which involves inflammation in the front part of the eye. It is often called iritis because it usually only affects the iris, the colored part of the eye. The inflammation may be associated with autoimmune diseases, but most cases occur in healthy people. The disorder may affect only one eye. It is most common in young and middle-aged people.
Posterior uveitis affects the back part of the uvea, and involves primarily the
Another form of uveitis is pars planitis. This inflammation affects the narrowed area (pars plana) between the colored part of the eye (iris) and the choroid. Pars planitis usually occurs in young men and is generally not associated with any other disease. However, some evidence suggests it may be linked to Crohn’s disease and possibly multiple sclerosis.
Uveitis can be associated with any of the following:
- Ankylosing spondylitis
- Behcet syndrome
CMV retinitis Herpes zoster infection Histoplasmosis
Kawasaki disease Psoriasis Reactive arthritis
- Rheumatoid arthritis
Toxoplasmosis Tuberculosis Ulcerative colitis
Uveitis can affect one or both eyes. Symptoms may develop rapidly and can include:
- Dark, floating spots in the vision
Eye pain Redness of the eye Sensitivity to light
Signs and tests
A complete medical history and eye examination should be performed. Laboratory tests may be done to rule out infection or an autoimmune disorder.
Persons over age 25 with pars planitis should have an MRI of their brain and spine to rule out multiple sclerosis.
Iritis is usually mild. Treatment may involve:
Eye drops that dilate the pupil to relieve pain
Steroid eye drops
Pars planitis is often treated with steroid eye drops. Other medicines, including steroids taken by mouth, may be prescribed to help suppress the immune system.
Posterior uveitis treatment depends on the underlying cause but almost always includes steroids taken by mouth. Additional specialists in infectious disease or autoimmunity may be needed for such diseases as syphilis, tuberculosis, AIDS, sarcoidosis, or Behcet syndrome.
If the uveitis is caused by a body-wide infection, treatment may involve antibiotics and powerful anti-inflammatory medicines called corticosteroids. See
With proper treatment, most attacks of anterior uveitis go away in a few days to weeks. However, relapses are common.
Inflammation related to posterior uveitis may last from months to years and may cause permanent vision damage, even with treatment.
- Fluid within the retina
Glaucoma Retinal detachment Vision loss
Calling your health care provider
Call for an appointment with your health care provider if you have symptoms of uveitis. Eye pain or reduced vision are urgent symptoms that require prompt medical attention.
Treatment of an underlying disorder may help to prevent uveitis in persons with a body-wide (systemic) infection or disease.